Mental Health and Substance Use Treatment in Millbury, MA
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 Supportive wife comforting husband with TRD during a meeting with a counselor in Millbury.

What Is Treatment-Resistant Depression?

March 08, 2024

After being found to have depression, you expect treatments to help alleviate symptoms like anxiety, desperation, and lack of energy. But, what do you do if traditional antidepressants don't seem to work or make things worse? If you have previously tried two or more treatments and still struggle with depression, you could have Treatment-Resistant Depression (TRD). Get more information about this disorder and see if you or a loved one could have Treatment-Resistant Depression.

How Are People Diagnosed With Treatment-Resistant Depression In Millbury?

Treatment-resistant depression describes patients with major depressive disorder (MDD) who have tried a minimum of two oral antidepressants to the proper duration and dosage levels without success. Although you may experience temporary mood improvements, they are most often succeeded by more symptoms. You might even discover that your episodes of depression are more prolonged and severe.

If antidepressants haven’t worked for you, it’s not unusual. According to the results of one study, between 29% and 46% of participants didn’t get lasting relief from oral antidepressants.

What Are The Symptoms Of Treatment-resistant Depression?

TRD is form of Major Depressive Disorder. Therefore, the symptoms of treatment-resistant depression are familiar, but you aren’t able to feel relief from standard antidepressants. These symptoms often include:

  • Constant hopelessness or sadness
  • Loss of interest or delight in activities
  • Changes in weight or appetite
  • Sleep difficulties like insomnia or lethargy
  • Feeling negatively about oneself.
  • Trouble focusing
  • Phantom joint pain, back pain, or headaches
  • Self-harm
  • Ongoing thoughts of suicide or death

It's critical to understand that the persistence and intensity of these symptoms, in spite of treatment, make TRD distinct from other kinds of depression. In addition, managing TRD typically demands a more multi-faceted type of depression treatment near Millbury, possibly including a mix of medications and psychotherapy.

SPRAVATO Approved For Treatment-Resistant Depression

SPRAVATO is the first FDA-approved nasal spray to treat adults with treatment-resistant depression. Esketamine is the active chemical ingredient and is considered to reduce symptoms by influencing specific brain circuits. In a clinical trial, people who were treated with Spravato and an oral antidepressant experienced a greater reduction in depressive symptoms after four weeks than participants who ingested a placebo with an antidepressant.

SPRAVATO is administered under the supervision of medical specialists at a facility approved through the Risk Evaluation and Mitigation Strategy (REMS) program. A comprehensive assessment of your medical background is needed in advance of beginning care. Potentially serious side effects could arise, including sedation and dissociation, and patients are required to be watched for two hours following treatment.

Consult With The Counseling Center At Millbury For Help With Treatment-resistant Depression in Millbury

Treatment-resistant depression can bring about an additional level of anxiety with feelings that your condition may not get better. Fortunately, a new approach to medication, psychotherapy, and professional support will help you work through TRD. The Counseling Center At Millbury is standing by to help. We offer a range of services for treatment-resistant depression and are an approved SPRAVATO treatment facility. Request help now by contacting us at 508-433-3866 or using the simple form on this page.